Protein profile

PA2607

hypothetical protein

Genome: NC_002516.2

Gene: PA2607 Structure source: AlphaFold UniProt Q9I0N1
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Amino acids 101
Annotations 3
Features 10
PDB binders 0
Druggability 0.66

Overview

Basic information about this protein and its source genome.

Accession
PA2607
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2607
Status
annotated
Amino acids
101
Structure source
AlphaFold
GO
GO:1990228 A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor). GO:0002143 The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps. GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.66
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MATTLHVLSRSPFNDGRLGSCLYLLNPGDGLLLCGDAVHALLAGSHACQALELMPAEIELFALLEDLQARGIEDVPARLVAVDYPGFVELATRFDKVNSWL

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:1990228 A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor).
  • GO:0002143 The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
4 100 SUPERFAMILY SSF75169 DsrEFH-like
4 100 InterPro IPR027396 DsrEFH-like
4 100 Gene3D G3DSA:3.40.1260.10 -
10 97 Pfam PF04077 DsrH like protein
10 97 InterPro IPR007215 Sulphur relay, TusB/DsrH
4 100 FunFam G3DSA:3.40.1260.10:FF:000005 Sulfur relay protein DsrH
2 100 PANTHER PTHR37526 PROTEIN TUSB
2 100 InterPro IPR007215 Sulphur relay, TusB/DsrH
5 100 NCBIfam TIGR03011 sulfurtransferase complex subunit TusB
5 100 InterPro IPR007215 Sulphur relay, TusB/DsrH

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2607
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.66