Protein profile

PA2650

hypothetical protein

Genome: NC_002516.2

Gene: PA2650 Structure source: AlphaFold UniProt Q9I0I8
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Amino acids 269
Annotations 2
Features 8
PDB binders 0
Druggability 0.85

Overview

Basic information about this protein and its source genome.

Accession
PA2650
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2650
Status
annotated
Amino acids
269
Structure source
AlphaFold
GO
GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0008757 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.85
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.
  • GO:0008757 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
68 162 Pfam PF08241 Methyltransferase domain
68 162 InterPro IPR013216 Methyltransferase type 11
66 166 CDD cd02440 AdoMet_MTases
55 200 SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases
55 200 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
15 167 PANTHER PTHR42912 METHYLTRANSFERASE
39 222 Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39
39 222 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2650
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.85