Protein profile

PA2659

hypothetical protein

Genome: NC_002516.2

Gene: PA2659 Structure source: AlphaFold UniProt Q9I0H9
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Amino acids 102
Annotations 0
Features 10
PDB binders 0
Druggability 0.671

Overview

Basic information about this protein and its source genome.

Accession
PA2659
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2659
Status
annotated
Amino acids
102
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.671
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MKKLTALFAATAIALTAGLAQARDLGPDEALKLRDAGTIKSFEELNKNAIAKHPGSSVHDTELEEEYGRYIYQVELRDPQGVKWDLELDAATGAVLKDHQDD

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
1 22 SignalP_EUK SignalP-noTM SignalP-noTM
42 98 Pfam PF03413 Peptidase propeptide and YPEB domain
42 98 InterPro IPR025711 PepSY domain
23 102 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
33 102 Gene3D G3DSA:3.10.450.40 -
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
16 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2659
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.671