Protein profile

PA2682

hypothetical protein

Genome: NC_002516.2

Gene: PA2682 Structure source: AlphaFold UniProt Q9I0F6
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Amino acids 413
Annotations 1
Features 12
PDB binders 0
Druggability 0.837

Overview

Basic information about this protein and its source genome.

Accession
PA2682
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2682
Status
annotated
Amino acids
413
Structure source
AlphaFold
GO
GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
27.604
Human E-value
1.14e-10
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.837
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
249 356 Pfam PF12680 SnoaL-like domain
249 356 InterPro IPR037401 SnoaL-like domain
2 230 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
2 230 InterPro IPR029058 Alpha/Beta hydrolase fold
2 231 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
2 231 InterPro IPR029058 Alpha/Beta hydrolase fold
3 233 PANTHER PTHR46623 CARBOXYMETHYLENEBUTENOLIDASE-RELATED
239 376 Gene3D G3DSA:3.10.450.50 -
16 230 Pfam PF01738 Dienelactone hydrolase family
16 230 InterPro IPR002925 Dienelactone hydrolase
238 380 SUPERFAMILY SSF54427 NTF2-like
238 380 InterPro IPR032710 NTF2-like domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2682
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.837
2 0.612