Protein profile

PA2707

hypothetical protein

Genome: NC_002516.2

Gene: PA2707 Structure source: AlphaFold UniProt Q9I0D5
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Amino acids 281
Annotations 2
Features 10
PDB binders 0
Druggability 0.748

Overview

Basic information about this protein and its source genome.

Accession
PA2707
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2707
Status
annotated
Amino acids
281
Structure source
AlphaFold
GO
GO:0005524 Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887 Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
26.667
Human E-value
7.7e-06
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.748
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MKFEGTQSYVATDDLKLAVNAAITLQRPLLVKGEPGTGKTMLAEQLAESFGAKLITWHIKSTTKAHQGLYEYDAVSRLRDSQLGVDKVHDVRNYIKKGKLWEAFEAEERVILLIDEIDKADIEFPNDLLQELDKMEFYVYETNETIKAKQRPIIIITSNNEKELPDAFLRRCFFHYIAFPDRETLQKIVDVHYPNIKQSLVSEALDIFFDVRKVPGLKKKPSTSELVDWLKLLMADEIGEAVLRERDPTKAIPPLAGALVKNEQDVQLLERLAFMSRRASR

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005524 Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
  • GO:0016887 Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
27 180 CDD cd00009 AAA
25 183 SMART SM00382 AAA_5
25 183 InterPro IPR003593 AAA+ ATPase domain
1 207 Gene3D G3DSA:3.40.50.300 -
1 207 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
29 173 Pfam PF00004 ATPase family associated with various cellular activities (AAA)
29 173 InterPro IPR003959 ATPase, AAA-type, core
8 249 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
8 249 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
3 194 PANTHER PTHR42759 MOXR FAMILY PROTEIN

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2707
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.748