Protein profile

PA2722

hypothetical protein

Genome: NC_002516.2

Gene: PA2722 Structure source: Experimental + AlphaFold UniProt Q9I0C0
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Amino acids 130
Annotations 2
Features 8
PDB binders 0
Druggability 0.442

Overview

Basic information about this protein and its source genome.

Accession
PA2722
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2722
Status
annotated
Amino acids
130
Structure source
Experimental + AlphaFold
GO
GO:0016846 Catalysis of the elimination of hydrogen sulfide or substituted H2S. GO:0046872 Binding to a metal ion.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.442
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0016846 Catalysis of the elimination of hydrogen sulfide or substituted H2S.
  • GO:0046872 Binding to a metal ion.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
3 123 SUPERFAMILY SSF51316 Mss4-like
3 123 InterPro IPR011057 Mss4-like superfamily
26 102 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme
26 102 InterPro IPR006913 CENP-V/GFA domain
4 120 PANTHER PTHR33337 GFA DOMAIN-CONTAINING PROTEIN
1 111 Gene3D G3DSA:3.90.1590.10 -
4 99 ProSiteProfiles PS51891 CENP-V/GFA domain profile.
4 99 InterPro IPR006913 CENP-V/GFA domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 8AJQ
X-ray 1.25 Å A,B,C,D,E,F,G,H
100.0% 1-130
PDBe RCSB PDBj File
Viewing
AlphaFold PA2722
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 21.78 0.874
2 4.85 0.217
3 1.28 0.013