Protein profile

PA2778

hypothetical protein

Genome: NC_002516.2

Gene: PA2778 Structure source: AlphaFold UniProt Q9I065
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Amino acids 293
Annotations 1
Features 10
PDB binders 0
Druggability 0.487

Overview

Basic information about this protein and its source genome.

Accession
PA2778
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2778
Status
annotated
Amino acids
293
Structure source
AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.487
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
15 151 CDD cd02549 Peptidase_C39A
15 151 InterPro IPR039563 Peptidase C39 single domain protein
154 276 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
154 276 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
10 118 Pfam PF13529 Peptidase_C39 like family
10 118 InterPro IPR039564 Peptidase C39-like
16 153 Gene3D G3DSA:3.90.70.10 Cysteine proteinases
7 261 NCBIfam NF033920 PA2778 family cysteine peptidase
165 265 SUPERFAMILY SSF48452 TPR-like
165 265 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2778
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.487
4 0.27
3 0.246