Protein profile

PA2785

hypothetical protein

Genome: NC_002516.2

Gene: PA2785 Structure source: AlphaFold UniProt Q9I058

Export view

Amino acids 72

Annotations 1

Features 13

PDB binders 0

Druggability 0.593

Overview

Basic information about this protein and its source genome.

Accession: PA2785
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA2785
Status: annotated
Amino acids: 72
Structure source: AlphaFold

GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.593

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records

Show feature table

Start	End	DB	Term	Name
12	62	CDD	cd00093	HTH_XRE
12	62	InterPro	IPR001387	Cro/C1-type helix-turn-helix domain
10	62	ProSiteProfiles	PS50943	Cro/C1-type HTH domain profile.
10	62	InterPro	IPR001387	Cro/C1-type helix-turn-helix domain
6	67	Pfam	PF13443	Cro/C1-type HTH DNA-binding domain
6	67	InterPro	IPR001387	Cro/C1-type helix-turn-helix domain
5	65	Gene3D	G3DSA:1.10.260.40	-
5	65	InterPro	IPR010982	Lambda repressor-like, DNA-binding domain superfamily
2	69	SUPERFAMILY	SSF47413	lambda repressor-like DNA-binding domains
2	69	InterPro	IPR010982	Lambda repressor-like, DNA-binding domain superfamily
9	62	SMART	SM00530	mbf_short4
9	62	InterPro	IPR001387	Cro/C1-type helix-turn-helix domain
1	66	PANTHER	PTHR37301	DNA-BINDING PROTEIN-RELATED

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA2785	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.593
3				0.378