Overview
Basic information about this protein and its source genome.
- Accession
- PA2797
- Gene
- PA2797
- Status
- annotated
- Amino acids
- 160
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- Y
- Localization
- Cytoplasmic
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
Gene Ontology (GO)
1- GO:0043856 The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 4 | 118 | ProSiteProfiles | PS50801 | STAS domain profile. |
| 4 | 118 | InterPro | IPR002645 | STAS domain |
| 3 | 108 | FunFam | G3DSA:3.30.750.24:FF:000039 | Putative anti-anti-sigma factor |
| 1 | 106 | PANTHER | PTHR33495 | ANTI-SIGMA FACTOR ANTAGONIST TM_1081-RELATED-RELATED |
| 6 | 106 | SUPERFAMILY | SSF52091 | SpoIIaa-like |
| 6 | 106 | InterPro | IPR036513 | STAS domain superfamily |
| 3 | 108 | Gene3D | G3DSA:3.30.750.24 | STAS domain |
| 3 | 108 | InterPro | IPR036513 | STAS domain superfamily |
| 1 | 160 | PIRSF | PIRSF029548 | UCP029548 |
| 1 | 160 | InterPro | IPR014557 | Uncharacterised conserved protein UCP029548, STAS-type |
| 6 | 106 | CDD | cd07043 | STAS_anti-anti-sigma_factors |
| 7 | 103 | Pfam | PF01740 | STAS domain |
| 7 | 103 | InterPro | IPR002645 | STAS domain |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA2797
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 3 | 0.847 | ||||||
| 1 | 0.395 |