Protein profile

PA2878

hypothetical protein

Genome: NC_002516.2

Gene: PA2878 Structure source: AlphaFold UniProt Q9HZW9
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Amino acids 213
Annotations 1
Features 7
PDB binders 0
Druggability 0.707

Overview

Basic information about this protein and its source genome.

Accession
PA2878
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2878
Status
annotated
Amino acids
213
Structure source
AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.707
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MPPTFIQRTRTNSLESLLYFLDPQMPHAALLLPPSASPLPEVVGFWRDAGPTLWFARNADFDRRFRERFTHLYELACANALRPAADEAEDHLGLLLLLDQYPRNAFRGTPRMYASDAQARRWAERALGQGLDRQVGDALRLFFYLPFAHAENLADQDRSVALNHGLGQPFLAHAREHREIIRRFGRFPHRNPILGRPSSAEELAFLAAGGFAG

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
114 213 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
114 213 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
36 113 Gene3D G3DSA:1.20.58.320 -
39 209 SUPERFAMILY SSF48452 TPR-like
39 209 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
45 210 Pfam PF06041 Bacterial protein of unknown function (DUF924)
45 210 InterPro IPR010323 Protein of unknown function DUF924

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2878
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.707