Protein profile

PA2880

hypothetical protein

Genome: NC_002516.2

Gene: PA2880 Structure source: AlphaFold UniProt Q9HZW7
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Amino acids 171
Annotations 0
Features 19
PDB binders 0
Druggability 0.868

Overview

Basic information about this protein and its source genome.

Accession
PA2880
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2880
Status
annotated
Amino acids
171
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.868
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

19 records
Show feature table
Start End DB Term Name
128 150 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
26 155 NCBIfam NF033665 multidrug/biocide efflux PACE transporter
31 53 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
53 57 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
26 154 NCBIfam NF033664 PACE efflux transporter
79 98 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
102 124 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
151 171 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
93 156 Pfam PF05232 Chlorhexidine efflux transporter
93 156 InterPro IPR007896 Chlorhexidine efflux transporter
25 88 Pfam PF05232 Chlorhexidine efflux transporter
25 88 InterPro IPR007896 Chlorhexidine efflux transporter
58 78 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
99 122 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
123 127 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 30 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
128 150 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
31 52 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
63 82 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2880
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.868
3 0.451