Protein profile

PA2946

hypothetical protein

Genome: NC_002516.2

Gene: NP_251636.2 Structure source: ColabFold
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Amino acids 233
Annotations 0
Features 23
PDB binders 0
Druggability 0.952

Overview

Basic information about this protein and its source genome.

Accession
PA2946
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
NP_251636.2
Status
annotated
Amino acids
233
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.952
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

23 records
Show feature table
Start End DB Term Name
107 126 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 226 NCBIfam TIGR02458 cobalt transporter subunit CbtA (proposed)
1 226 InterPro IPR012666 Cobalt transporter subunit CbtA, putative
79 98 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
105 123 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
124 142 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
141 163 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
161 164 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
1 11 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
34 78 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
165 182 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
78 100 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
201 224 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
12 33 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
165 181 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
9 31 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
202 224 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
225 233 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
182 200 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
143 160 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
99 104 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
2 224 Pfam PF09490 Probable cobalt transporter subunit (CbtA)
2 224 InterPro IPR012666 Cobalt transporter subunit CbtA, putative

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold PA2946
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.952