Protein profile

PA3064

hypothetical protein

Genome: NC_002516.2

Gene: pelA PA3064 Structure source: Experimental + AlphaFold UniProt Q9HZE4
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Amino acids 948
Annotations 4
Features 26
PDB binders 0
Druggability 0.652

Overview

Basic information about this protein and its source genome.

Accession
PA3064
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
pelA PA3064
Status
annotated
Amino acids
948
Structure source
Experimental + AlphaFold
GO
GO:0019213 Catalysis of the hydrolysis of an acetyl group from a substrate molecule. GO:0000271 The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:0044010 A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. GO:0005975 The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.652
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4
  • GO:0019213 Catalysis of the hydrolysis of an acetyl group from a substrate molecule.
  • GO:0000271 The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
  • GO:0044010 A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
  • GO:0005975 The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

Sequence Features

Domain/signature hits from InterPro and related databases.

26 records
Show feature table
Start End DB Term Name
73 291 Pfam PF03537 Glycoside-hydrolase family GH114
73 291 InterPro IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain
570 787 SUPERFAMILY SSF88713 Glycoside hydrolase/deacetylase
570 787 InterPro IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel
253 263 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature
253 263 InterPro IPR016062 Hypothetical protein TM1410-related
275 287 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature
275 287 InterPro IPR016062 Hypothetical protein TM1410-related
147 166 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature
147 166 InterPro IPR016062 Hypothetical protein TM1410-related
90 109 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature
90 109 InterPro IPR016062 Hypothetical protein TM1410-related
39 45 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
53 311 Gene3D G3DSA:3.20.20.70 Aldolase class I
53 311 InterPro IPR013785 Aldolase-type TIM barrel
20 946 PANTHER PTHR35882 PELA
5 948 PIRSF PIRSF029570 UCP029570
5 948 InterPro IPR016925 Uncharacterised conserved protein UCP029570
27 38 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 26 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
25 47 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
52 305 SUPERFAMILY SSF51445 (Trans)glycosidases
52 305 InterPro IPR017853 Glycoside hydrolase superfamily
518 784 CDD cd10922 CE4_PelA_like_C
1 45 Phobius SIGNAL_PEPTIDE Signal peptide region
46 948 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

3 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 9CGY
X-ray 2.09 Å A
94.8% 49-947
PDBe RCSB PDBj File
Viewing
PDB 5TCB
X-ray 1.53 Å A
27.1% 47-303
PDBe RCSB PDBj File
Loaded
PDB 5TSY
X-ray 1.90 Å A
27.1% 47-303
PDBe RCSB PDBj File
Loaded
AlphaFold PA3064
AlphaFold — — full sequence — Loaded
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