Target Pathogen

Overview

Basic information about this protein and its source genome.

Accession: PA3080
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3080
Status: annotated
Amino acids: 365
Structure source: AlphaFold

GO

GO:0009523 A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center. GO:0015979 The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds. GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.754

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3

GO:0009523 A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center.
GO:0015979 The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.
GO:0005515 Binding to a protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records

Show feature table

Start	End	DB	Term	Name
78	323	SUPERFAMILY	SSF110296	Oligoxyloglucan reducing end-specific cellobiohydrolase
1	32	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
33	44	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.
150	276	Pfam	PF14870	Photosynthesis system II assembly factor YCF48
150	276	InterPro	IPR028203	Photosynthesis system II assembly factor Ycf48/Hcf136-like domain
45	52	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
53	365	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
19	355	PANTHER	PTHR47199	PHOTOSYSTEM II STABILITY/ASSEMBLY FACTOR HCF136, CHLOROPLASTIC
1	24	MobiDBLite	mobidb-lite	consensus disorder prediction
1	52	SignalP_EUK	SignalP-noTM	SignalP-noTM
1	52	SignalP_GRAM_POSITIVE	SignalP-TM	SignalP-TM
97	305	CDD	cd15482	Sialidase_non-viral
41	290	Gene3D	G3DSA:2.130.10.10	-
41	290	InterPro	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
1	52	Phobius	SIGNAL_PEPTIDE	Signal peptide region

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3080	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.754

PA3080