Protein profile

PA3125

hypothetical protein

Genome: NC_002516.2

Gene: PA3125 Structure source: AlphaFold UniProt Q9HZ99
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Amino acids 442
Annotations 1
Features 15
PDB binders 0
Druggability 0.769

Overview

Basic information about this protein and its source genome.

Accession
PA3125
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3125
Status
annotated
Amino acids
442
Structure source
AlphaFold
GO
GO:0016788 Catalysis of the hydrolysis of any ester bond.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.769
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016788 Catalysis of the hydrolysis of any ester bond.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
183 425 Gene3D G3DSA:3.40.50.1110 SGNH hydrolase
183 425 InterPro IPR036514 SGNH hydrolase superfamily
1 33 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
218 413 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family
218 413 InterPro IPR013830 SGNH hydrolase-type esterase domain
1 17 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
5 429 PANTHER PTHR43784 GDSL-LIKE LIPASE/ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED
212 419 SUPERFAMILY SSF52266 SGNH hydrolase
50 442 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 49 Phobius SIGNAL_PEPTIDE Signal peptide region
1 29 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
18 31 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 30 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
214 422 CDD cd01830 XynE_like
32 49 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3125
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.769