Protein profile

PA3238

hypothetical protein

Genome: NC_002516.2

Gene: PA3238 Structure source: AlphaFold UniProt Q9HZ02
Amino acids 453
Annotations 1
Features 16
PDB binders 0
Druggability 0.932

Overview

Basic information about this protein and its source genome.

Accession
PA3238
Gene
PA3238
Status
annotated
Amino acids
453
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.932
Structure
Pocket

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
1 437 InterPro IPR007428 MlaA lipoprotein
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
20 24 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 24 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
25 453 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
88 419 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
88 419 InterPro IPR029058 Alpha/Beta hydrolase fold
1 24 Phobius SIGNAL_PEPTIDE Signal peptide region
1 24 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
86 434 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
86 434 InterPro IPR029058 Alpha/Beta hydrolase fold
1 437 PANTHER PTHR30035 LIPOPROTEIN VACJ-RELATED
1 18 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
8 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
103 420 Pfam PF12697 Alpha/beta hydrolase family
103 420 InterPro IPR000073 Alpha/beta hydrolase fold-1

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3238
AlphaFold full sequence Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.932