Protein profile

PA3251

hypothetical protein

Genome: NC_002516.2

Gene: PA3251 Structure source: AlphaFold UniProt Q9HYY9

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Amino acids 269

Annotations 1

Features 7

PDB binders 0

Druggability 0.493

Overview

Basic information about this protein and its source genome.

Accession: PA3251
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3251
Status: annotated
Amino acids: 269
Structure source: AlphaFold

GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Target profile

Computed evidence for target prioritization.

Human off-target: hit
Human identity (%): 24.648
Human E-value: 1.54e-11
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.493

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records

Show feature table

Start	End	DB	Term	Name
4	209	PANTHER	PTHR10151	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE
2	255	SUPERFAMILY	SSF53649	Alkaline phosphatase-like
2	255	InterPro	IPR017850	Alkaline-phosphatase-like, core domain superfamily
1	248	Gene3D	G3DSA:3.40.720.10	Alkaline Phosphatase, subunit A
1	248	InterPro	IPR017850	Alkaline-phosphatase-like, core domain superfamily
5	210	Pfam	PF01663	Type I phosphodiesterase / nucleotide pyrophosphatase
5	210	InterPro	IPR002591	Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3251	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.493