Protein profile

PA3304

hypothetical protein

Genome: NC_002516.2

Gene: PA3304 Structure source: AlphaFold UniProt Q9HYU0
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Amino acids 285
Annotations 3
Features 15
PDB binders 0
Druggability 0.949

Overview

Basic information about this protein and its source genome.

Accession
PA3304
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3304
Status
annotated
Amino acids
285
Structure source
AlphaFold
GO
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857 Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085 The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.949
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
  • GO:0022857 Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
  • GO:0055085 The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
29 285 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
4 284 PANTHER PTHR30367 P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED
1 10 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
42 222 SUPERFAMILY SSF111369 HlyD-like secretion proteins
7 29 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
153 236 Pfam PF13437 HlyD family secretion protein
120 154 Coils Coil Coil
42 109 Gene3D G3DSA:2.40.50.100 -
1 6 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
42 235 NCBIfam TIGR01730 efflux RND transporter periplasmic adaptor subunit
42 235 InterPro IPR006143 RND efflux pump, membrane fusion protein
166 285 Gene3D G3DSA:2.40.30.170 -
43 88 Pfam PF13533 Biotin-lipoyl like
43 88 InterPro IPR039562 Membrane fusion protein, biotin-lipoyl like domain
7 28 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3304
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.949
4 0.358
2 0.306
9 0.249