Target Pathogen

Overview

Basic information about this protein and its source genome.

Accession: PA3334
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3334
Status: annotated
Amino acids: 79
Structure source: AlphaFold

GO

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0000035 Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid. GO:0000036 Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis. GO:0009245 The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

5 GO

Gene Ontology (GO)

5

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:0000035 Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
GO:0000036 Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.
GO:0009245 The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
9	72	Pfam	PF00550	Phosphopantetheine attachment site
9	72	InterPro	IPR009081	Phosphopantetheine binding ACP domain
3	77	SUPERFAMILY	SSF47336	ACP-like
3	77	InterPro	IPR036736	ACP-like superfamily
2	78	Gene3D	G3DSA:1.10.1200.10	-
2	78	InterPro	IPR036736	ACP-like superfamily
3	77	ProSiteProfiles	PS50075	Carrier protein (CP) domain profile.
3	77	InterPro	IPR009081	Phosphopantetheine binding ACP domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

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Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3334	AlphaFold	—	—	full sequence	—	Viewing