Protein profile

PA3335

hypothetical protein

Genome: NC_002516.2

Gene: PA3335 Structure source: Experimental + AlphaFold UniProt Q9HYR0
Amino acids 250
Annotations 0
Features 5
PDB binders 0
Druggability 0.844

Overview

Basic information about this protein and its source genome.

Accession
PA3335
Gene
PA3335
Status
annotated
Amino acids
250
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.844
Structure
Pocket

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
60 115 CDD cd02440 AdoMet_MTases
15 225 SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases
15 225 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
16 232 Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39
16 232 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

3 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 8RYE
X-ray 1.95 Å A,B,C,D
99.6% 2-250
Viewing
PDB 8RYF
X-ray 1.95 Å A,B
99.6% 2-250
Loaded
PDB 8RYD
X-ray 3.00 Å A,B,C,D
99.6% 2-250
Loaded
AlphaFold PA3335
AlphaFold full sequence Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.844

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 17.21 0.798