Protein profile

PA3368

acetyltransferase

Genome: NC_002516.2

Gene: PA3368 Structure source: AlphaFold UniProt Q9HYN3

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Amino acids 221

Annotations 2

Features 10

PDB binders 0

Druggability 0.819

Overview

Basic information about this protein and its source genome.

Accession: PA3368
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3368
Status: annotated
Amino acids: 221
Structure source: AlphaFold

GO:0008080 Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. GO:0016747 Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.819

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0008080 Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.
GO:0016747 Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records

Show feature table

Start	End	DB	Term	Name
109	209	Pfam	PF00583	Acetyltransferase (GNAT) family
109	209	InterPro	IPR000182	GNAT domain
77	216	SUPERFAMILY	SSF55729	Acyl-CoA N-acyltransferases (Nat)
77	216	InterPro	IPR016181	Acyl-CoA N-acyltransferase
77	215	PANTHER	PTHR43877	-
77	218	Gene3D	G3DSA:3.40.630.30	-
77	218	FunFam	G3DSA:3.40.630.30:FF:000144	Putatative acetyltransferase
125	192	CDD	cd04301	NAT_SF
79	221	ProSiteProfiles	PS51186	Gcn5-related N-acetyltransferase (GNAT) domain profile.
79	221	InterPro	IPR000182	GNAT domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3368	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.819