Amino acids
387
Annotations
2
Features
14
PDB binders
0
Overview
Basic information about this protein and its source genome.
- Accession
- PA3374
- Gene
- PA3374
- Status
- annotated
- Amino acids
- 387
- Structure source
- AlphaFold
GO
GO:0016810 Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
GO:0019700 The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Cytoplasmic
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
2 GO
Gene Ontology (GO)
2- GO:0016810 Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
- GO:0019700 The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
Sequence Features
Domain/signature hits from InterPro and related databases.
14 records
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 179 | 387 | Pfam | PF07969 | Amidohydrolase family |
| 179 | 387 | InterPro | IPR013108 | Amidohydrolase 3 |
| 54 | 353 | SUPERFAMILY | SSF51556 | Metallo-dependent hydrolases |
| 54 | 353 | InterPro | IPR032466 | Metal-dependent hydrolase |
| 6 | 387 | NCBIfam | TIGR02318 | phosphonate metabolism protein PhnM |
| 6 | 387 | InterPro | IPR012696 | Phosphonate metabolism PhnM |
| 52 | 383 | CDD | cd01306 | PhnM |
| 52 | 383 | InterPro | IPR012696 | Phosphonate metabolism PhnM |
| 3 | 386 | PANTHER | PTHR43135 | ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE |
| 3 | 385 | SUPERFAMILY | SSF51338 | Composite domain of metallo-dependent hydrolases |
| 3 | 385 | InterPro | IPR011059 | Metal-dependent hydrolase, composite domain superfamily |
| 1 | 272 | Gene3D | G3DSA:3.20.20.140 | - |
| 3 | 387 | PIRSF | PIRSF038971 | PhnM |
| 3 | 387 | InterPro | IPR012696 | Phosphonate metabolism PhnM |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
No pockets are loaded yet for the displayed AlphaFold model PA3374 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.
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Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA3374
|
AlphaFold | — | — | full sequence | — | Viewing |