Protein profile

PA3396

acessory protein NosL

Genome: NC_002516.2

Gene: PA3396 nosL Structure source: AlphaFold UniProt Q9HYK8

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Amino acids 178

Annotations 0

Features 15

PDB binders 0

Druggability 0.824

Overview

Basic information about this protein and its source genome.

Accession: PA3396
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3396 nosL
Status: annotated
Amino acids: 178
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.824

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records

Show feature table

Start	End	DB	Term	Name
1	22	SignalP_GRAM_NEGATIVE	SignalP-noTM	SignalP-noTM
27	178	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1	10	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
1	24	ProSiteProfiles	PS51257	Prokaryotic membrane lipoprotein lipid attachment site profile.
1	26	Phobius	SIGNAL_PEPTIDE	Signal peptide region
59	117	Gene3D	G3DSA:3.30.70.2060	-
36	163	Pfam	PF05573	NosL
36	163	InterPro	IPR008719	Nitrous oxide reductase accessory protein NosL
22	26	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
1	176	PANTHER	PTHR41247	HTH-TYPE TRANSCRIPTIONAL REPRESSOR YCNK
1	176	InterPro	IPR008719	Nitrous oxide reductase accessory protein NosL
11	21	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.
1	26	SignalP_EUK	SignalP-noTM	SignalP-noTM
66	172	SUPERFAMILY	SSF160387	NosL/MerB-like
118	175	Gene3D	G3DSA:3.30.70.2050	-

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3396	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.824