Overview
Basic information about this protein and its source genome.
- Accession
- PA3402
- Gene
- PA3402
- Status
- annotated
- Amino acids
- 323
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- CytoplasmicMembrane
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 25 | 323 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. |
| 6 | 24 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. |
| 72 | 92 | Coils | Coil | Coil |
| 7 | 24 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. |
| 40 | 286 | Pfam | PF16576 | Barrel-sandwich domain of CusB or HlyD membrane-fusion |
| 40 | 286 | InterPro | IPR032317 | RND efflux pump, membrane fusion protein, barrel-sandwich domain |
| 105 | 132 | Coils | Coil | Coil |
| 107 | 165 | SUPERFAMILY | SSF111369 | HlyD-like secretion proteins |
| 176 | 203 | Coils | Coil | Coil |
| 1 | 5 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. |
| 103 | 167 | Gene3D | G3DSA:1.10.287.470 | Helix hairpin bin |
| 73 | 95 | Gene3D | G3DSA:1.10.287.470 | Helix hairpin bin |
| 214 | 322 | Gene3D | G3DSA:2.40.30.170 | - |
| 40 | 94 | SUPERFAMILY | SSF111369 | HlyD-like secretion proteins |
| 4 | 319 | PANTHER | PTHR30438 | UNCHARACTERIZED |
| 174 | 253 | SUPERFAMILY | SSF111369 | HlyD-like secretion proteins |
| 39 | 72 | Gene3D | G3DSA:2.40.50.100 | - |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA3402
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 13 | 0.311 |