Protein profile

PA3464

hypothetical protein

Genome: NC_002516.2

Gene: PA3464 Structure source: AlphaFold UniProt Q9HYE2
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Amino acids 441
Annotations 1
Features 11
PDB binders 0
Druggability 0.938

Overview

Basic information about this protein and its source genome.

Accession
PA3464
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3464
Status
annotated
Amino acids
441
Structure source
AlphaFold
GO
GO:0016788 Catalysis of the hydrolysis of any ester bond.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.938
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016788 Catalysis of the hydrolysis of any ester bond.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
22 441 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
167 322 Gene3D G3DSA:1.10.575.10 P1 Nuclease
167 322 InterPro IPR008947 Phospholipase C/P1 nuclease domain superfamily
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
1 21 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
3 14 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
15 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
147 366 SUPERFAMILY SSF48537 Phospholipase C/P1 nuclease
147 366 InterPro IPR008947 Phospholipase C/P1 nuclease domain superfamily
1 23 SignalP_EUK SignalP-noTM SignalP-noTM
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3464
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.938