Protein profile

PA3513

hypothetical protein

Genome: NC_002516.2

Gene: PA3513 Structure source: AlphaFold UniProt Q9HY96
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Amino acids 335
Annotations 1
Features 14
PDB binders 0
Druggability 0.828

Overview

Basic information about this protein and its source genome.

Accession
PA3513
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3513
Status
annotated
Amino acids
335
Structure source
AlphaFold
GO
GO:0009228 The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.828
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0009228 The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
39 321 Gene3D G3DSA:3.40.190.10 -
1 23 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
39 250 Pfam PF09084 NMT1/THI5 like
39 250 InterPro IPR015168 SsuA/THI5-like
1 326 PANTHER PTHR31528 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE SYNTHASE THI11-RELATED
1 326 InterPro IPR027939 NMT1/THI5 family
1 23 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
24 335 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 23 Phobius SIGNAL_PEPTIDE Signal peptide region
20 23 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
36 256 SUPERFAMILY SSF53850 Periplasmic binding protein-like II
110 210 Gene3D G3DSA:3.40.190.10 -
8 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3513
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.828
7 0.222