Protein profile

PA3519

hypothetical protein

Genome: NC_002516.2

Gene: PA3519 Structure source: AlphaFold UniProt Q9HY90
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Amino acids 345
Annotations 3
Features 12
PDB binders 0
Druggability 0.491

Overview

Basic information about this protein and its source genome.

Accession
PA3519
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3519
Status
annotated
Amino acids
345
Structure source
AlphaFold
GO
GO:0042597 The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). GO:0004553 Catalysis of the hydrolysis of any O-glycosyl bond. GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.491
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0042597 The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
  • GO:0004553 Catalysis of the hydrolysis of any O-glycosyl bond.
  • GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
118 341 Gene3D G3DSA:1.20.910.10 -
118 341 InterPro IPR016084 Haem oxygenase-like, multi-helical
120 334 SUPERFAMILY SSF48613 Heme oxygenase-like
120 334 InterPro IPR016084 Haem oxygenase-like, multi-helical
84 344 PANTHER PTHR40279 PQQC-LIKE PROTEIN
84 344 InterPro IPR039068 Pyrroloquinoline-quinone synthase-like
187 289 SMART SM01236 Haem_oxygenas_2_2
154 321 Pfam PF14518 Iron-containing redox enzyme
19 106 Pfam PF14515 Haem-oxygenase-associated N-terminal helices
19 106 InterPro IPR029474 Haem-oxygenase-associated, N-terminal helices
20 106 Gene3D G3DSA:1.10.1240.20 Lytic transglycosylase, superhelical linker domain
20 106 InterPro IPR037061 Lytic transglycosylase, superhelical linker domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3519
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
8 0.491
4 0.245
1 0.237