Protein profile

PA3619

hypothetical protein

Genome: NC_002516.2

Gene: PA3619 Structure source: AlphaFold UniProt Q9HY09

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Amino acids 335

Annotations 0

Features 14

PDB binders 0

Druggability 0.834

Overview

Basic information about this protein and its source genome.

Accession: PA3619
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3619
Status: annotated
Amino acids: 335
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.834

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records

Show feature table

Start	End	DB	Term	Name
1	27	SignalP_GRAM_NEGATIVE	SignalP-noTM	SignalP-noTM
1	27	Phobius	SIGNAL_PEPTIDE	Signal peptide region
1	7	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
19	27	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
28	335	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
8	18	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.
31	260	Gene3D	G3DSA:2.120.10.30	-
31	260	InterPro	IPR011042	Six-bladed beta-propeller, TolB-like
1	22	SignalP_EUK	SignalP-noTM	SignalP-noTM
56	236	PANTHER	PTHR36842	PROTEIN TOLB HOMOLOG
1	27	SignalP_GRAM_POSITIVE	SignalP-TM	SignalP-TM
91	110	Pfam	PF07676	WD40-like Beta Propeller Repeat
91	110	InterPro	IPR011659	WD40-like beta propeller
45	313	SUPERFAMILY	SSF69304	Tricorn protease N-terminal domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3619	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.834
2				0.826