Protein profile

PA3647

hypothetical protein

Genome: NC_002516.2

Gene: PA3647 Structure source: AlphaFold UniProt Q9HXY5
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Amino acids 168
Annotations 2
Features 20
PDB binders 0
Druggability 0.937

Overview

Basic information about this protein and its source genome.

Accession
PA3647
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3647
Status
annotated
Amino acids
168
Structure source
AlphaFold
GO
GO:0051082 Binding to an unfolded protein. GO:0050821 Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.937
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0051082 Binding to an unfolded protein.
  • GO:0050821 Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.

Sequence Features

Domain/signature hits from InterPro and related databases.

20 records
Show feature table
Start End DB Term Name
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
4 14 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
7 29 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
22 165 SUPERFAMILY SSF111384 OmpH-like
22 165 InterPro IPR024930 Skp domain superfamily
22 164 FunFam G3DSA:3.30.910.20:FF:000002 Outer membrane chaperone Skp (OmpH)
1 166 PANTHER PTHR35089 CHAPERONE PROTEIN SKP
1 166 InterPro IPR005632 Chaperone protein Skp
25 164 Pfam PF03938 Outer membrane protein (OmpH-like)
25 164 InterPro IPR005632 Chaperone protein Skp
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
15 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 22 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
23 168 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
11 165 SMART SM00935 OmpH_2
11 165 InterPro IPR005632 Chaperone protein Skp
59 79 Coils Coil Coil
22 164 Gene3D G3DSA:3.30.910.20 Skp domain
22 164 InterPro IPR024930 Skp domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3647
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.937
4 0.87
6 0.734
3 0.317