Protein profile

PA3697

hypothetical protein

Genome: NC_002516.2

Gene: PA3697 Structure source: AlphaFold UniProt Q9HXU3

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Amino acids 431

Annotations 3

Features 8

PDB binders 0

Druggability 0.79

Overview

Basic information about this protein and its source genome.

Accession: PA3697
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3697
Status: annotated
Amino acids: 431
Structure source: AlphaFold

GO:0008237 Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0006508 The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. GO:0080164 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.79

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

GO:0008237 Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0006508 The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0080164 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
41	419	SMART	SM01154	DUF1704_2
41	419	InterPro	IPR012548	Microtubule-associated tyrosine carboxypeptidase
4	426	PANTHER	PTHR31817	-
4	426	InterPro	IPR012548	Microtubule-associated tyrosine carboxypeptidase
42	416	Pfam	PF08014	Domain of unknown function (DUF1704)
42	416	InterPro	IPR012548	Microtubule-associated tyrosine carboxypeptidase
21	412	NCBIfam	TIGR02421	flavohemoglobin expression-modulating QEGLA motif protein
21	412	InterPro	IPR012656	Conserved hypothetical protein CHP02421, QEGLA

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3697	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
4				0.79
1				0.33