Protein profile

PA3789

hypothetical protein

Genome: NC_002516.2

Gene: PA3789 IPC1295_13560 Structure source: AlphaFold UniProt P72122 UniProt G3XCX0
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Amino acids 471
Annotations 0
Features 24
PDB binders 0
Druggability 0.903

Overview

Basic information about this protein and its source genome.

Accession
PA3789
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3789 IPC1295_13560
Status
annotated
Amino acids
471
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.903
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

24 records
Show feature table
Start End DB Term Name
409 427 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
196 218 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
20 42 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
43 146 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
312 334 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
147 167 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
387 408 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
432 454 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
11 468 PANTHER PTHR34219 IRON-REGULATED INNER MEMBRANE PROTEIN-RELATED
11 468 InterPro IPR005625 PepSY-associated TM protein
219 386 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
255 286 MobiDBLite mobidb-lite consensus disorder prediction
150 167 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
168 195 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 19 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
461 471 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
428 460 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
16 410 Pfam PF03929 PepSY-associated TM region
16 410 InterPro IPR005625 PepSY-associated TM protein
299 355 Pfam PF03413 Peptidase propeptide and YPEB domain
299 355 InterPro IPR025711 PepSY domain
196 218 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
20 42 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
386 408 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3789
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.903
1 0.354
2 0.24