Protein profile

PA3822

preprotein translocase subunit YajC

Genome: NC_002516.2

Gene: PA3822 Structure source: AlphaFold UniProt Q9HXI0
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Amino acids 112
Annotations 2
Features 20
PDB binders 0
Druggability 0.57

Overview

Basic information about this protein and its source genome.

Accession
PA3822
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3822
Status
annotated
Amino acids
112
Structure source
AlphaFold
GO
GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0015031 The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.57
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
  • GO:0015031 The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Sequence Features

Domain/signature hits from InterPro and related databases.

20 records
Show feature table
Start End DB Term Name
3 10 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
22 104 SMART SM01323 YajC_2
22 104 InterPro IPR003849 Preprotein translocase YajC
19 27 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
45 112 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
27 104 NCBIfam TIGR00739 preprotein translocase subunit YajC
27 104 InterPro IPR003849 Preprotein translocase YajC
11 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
28 44 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
28 101 Pfam PF02699 Preprotein translocase subunit
28 101 InterPro IPR003849 Preprotein translocase YajC
22 107 PANTHER PTHR33909 SEC TRANSLOCON ACCESSORY COMPLEX SUBUNIT YAJC
22 107 InterPro IPR003849 Preprotein translocase YajC
24 44 PRINTS PR01853 Bacterial YajC preprotein translocase signature
24 44 InterPro IPR003849 Preprotein translocase YajC
62 80 PRINTS PR01853 Bacterial YajC preprotein translocase signature
62 80 InterPro IPR003849 Preprotein translocase YajC
20 42 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3822
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.57
2 0.384