Protein profile

PA3848

hypothetical protein

Genome: NC_002516.2

Gene: PA3848 Structure source: AlphaFold UniProt Q9HXF8
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Amino acids 451
Annotations 0
Features 16
PDB binders 0
Druggability 0.813

Overview

Basic information about this protein and its source genome.

Accession
PA3848
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3848
Status
annotated
Amino acids
451
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.813
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
390 410 Coils Coil Coil
46 319 Pfam PF16868 NMT1-like family
46 319 InterPro IPR011852 TRAP transporter solute receptor, TAXI family
46 319 Gene3D G3DSA:3.40.190.10 -
340 362 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
123 264 FunFam G3DSA:3.40.190.10:FF:000300 C4-dicarboxylate ABC transporter substrate-binding protein
1 11 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
41 319 SUPERFAMILY SSF53850 Periplasmic binding protein-like II
37 339 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
123 264 Gene3D G3DSA:3.40.190.10 -
24 276 PANTHER PTHR42941 SLL1037 PROTEIN
24 276 InterPro IPR011852 TRAP transporter solute receptor, TAXI family
340 362 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
363 451 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
13 35 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
12 36 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3848
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
10 0.813
1 0.784
19 0.25