Protein profile

PA3849

nucleoid-associated protein NdpA

Genome: NC_002516.2

Gene: PA3849 Structure source: AlphaFold UniProt Q9HXF7
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Amino acids 334
Annotations 5
Features 6
PDB binders 0
Druggability 0.576

Overview

Basic information about this protein and its source genome.

Accession
PA3849
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3849
Status
annotated
Amino acids
334
Structure source
AlphaFold
GO
GO:0043590 The region of a bacterial cell to which the DNA is confined. GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0003690 Binding to double-stranded DNA. GO:0003727 Binding to single-stranded RNA. GO:0009295 The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.576
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

5 GO

Gene Ontology (GO)

5
  • GO:0043590 The region of a bacterial cell to which the DNA is confined.
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
  • GO:0003690 Binding to double-stranded DNA.
  • GO:0003727 Binding to single-stranded RNA.
  • GO:0009295 The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
2 333 PANTHER PTHR38772 -
2 333 InterPro IPR007358 Nucleoid-associated protein NdpA
1 332 Hamap MF_00730 Nucleoid-associated protein YejK [yejK].
1 332 InterPro IPR007358 Nucleoid-associated protein NdpA
7 326 Pfam PF04245 37-kD nucleoid-associated bacterial protein
7 326 InterPro IPR007358 Nucleoid-associated protein NdpA

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3849
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.576
4 0.549