Protein profile

PA3855

hypothetical protein

Genome: NC_002516.2

Gene: PA3855 Structure source: AlphaFold UniProt Q9HXF1

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Amino acids 233

Annotations 0

Features 14

PDB binders 0

Druggability 0.833

Overview

Basic information about this protein and its source genome.

Accession: PA3855
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3855
Status: annotated
Amino acids: 233
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: hit
Human identity (%): 30.932
Human E-value: 2.22e-30
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.833

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records

Show feature table

Start	End	DB	Term	Name
1	232	SFLD	SFLDG01180	SUF1
1	102	SUPERFAMILY	SSF52833	Thioredoxin-like
1	102	InterPro	IPR036249	Thioredoxin-like superfamily
1	75	CDD	cd03080	GST_N_Metaxin_like
164	226	Pfam	PF17171	Glutathione S-transferase, C-terminal domain
164	226	InterPro	IPR033468	Metaxin, glutathione S-transferase domain
1	232	SFLD	SFLDG01200	SUF1.1
1	232	InterPro	IPR026928	FAX/IsoI-like
135	228	Gene3D	G3DSA:1.20.1050.10	-
2	232	PANTHER	PTHR12289	METAXIN RELATED
18	114	Pfam	PF17172	Glutathione S-transferase N-terminal domain
18	114	InterPro	IPR012336	Thioredoxin-like fold
158	229	SUPERFAMILY	SSF47616	GST C-terminal domain-like
158	229	InterPro	IPR036282	Glutathione S-transferase, C-terminal domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3855	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.833