Protein profile

PA3864

transcriptional regulator

Genome: NC_002516.2

Gene: PA3864 dauR Structure source: AlphaFold UniProt Q9HXE2

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Amino acids 210

Annotations 2

Features 6

PDB binders 0

Druggability 0.464

Overview

Basic information about this protein and its source genome.

Accession: PA3864
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA3864 dauR
Status: annotated
Amino acids: 210
Structure source: AlphaFold

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.464

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records

Show feature table

Start	End	DB	Term	Name
2	208	PANTHER	PTHR35568	TRANSCRIPTIONAL REGULATOR DAUR
2	208	InterPro	IPR039446	Transcriptional regulator DauR-like
9	114	Pfam	PF08348	YheO-like PAS domain
9	114	InterPro	IPR013559	YheO-like
142	203	Pfam	PF13309	HTH domain
142	203	InterPro	IPR039445	Transcriptional regulator DauR-like, HTH domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA3864	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
3				0.464