Protein profile

PA3919

hypothetical protein

Genome: NC_002516.2

Gene: PA3919 Structure source: AlphaFold UniProt Q9HX94
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Amino acids 463
Annotations 2
Features 17
PDB binders 0
Druggability 0.354

Overview

Basic information about this protein and its source genome.

Accession
PA3919
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3919
Status
annotated
Amino acids
463
Structure source
AlphaFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0005524 Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.354
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
  • GO:0005524 Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

Sequence Features

Domain/signature hits from InterPro and related databases.

17 records
Show feature table
Start End DB Term Name
252 461 Gene3D G3DSA:3.40.50.300 -
252 461 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
10 162 FunFam G3DSA:3.40.50.1010:FF:000007 PhoH family protein
13 147 SMART SM00670 PIN_9
13 147 InterPro IPR002716 PIN domain
15 462 PANTHER PTHR30473 PROTEIN PHOH
250 462 FunFam G3DSA:3.40.50.300:FF:000013 PhoH family ATPase
12 161 SUPERFAMILY SSF88723 PIN domain-like
12 161 InterPro IPR029060 PIN-like domain superfamily
254 444 Pfam PF02562 PhoH-like protein
254 444 InterPro IPR003714 PhoH-like protein
9 163 Gene3D G3DSA:3.40.50.1010 -
208 442 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
208 442 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
15 160 Pfam PF13638 PIN domain
15 160 InterPro IPR002716 PIN domain
14 163 CDD cd09883 PIN_VapC_PhoHL-ATPase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3919
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
6 0.354
10 0.281