Protein profile

PA3943

hypothetical protein

Genome: NC_002516.2

Gene: PA3943 Structure source: AlphaFold UniProt Q9HX73
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Amino acids 531
Annotations 1
Features 11
PDB binders 0
Druggability 0.768

Overview

Basic information about this protein and its source genome.

Accession
PA3943
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3943
Status
annotated
Amino acids
531
Structure source
AlphaFold
GO
GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.768
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
74 231 CDD cd02142 McbC_SagB-like_oxidoreductase
100 229 SUPERFAMILY SSF55469 FMN-dependent nitroreductase-like
100 229 InterPro IPR000415 Nitroreductase-like
28 265 Gene3D G3DSA:3.40.109.10 NADH Oxidase
28 265 InterPro IPR000415 Nitroreductase-like
299 523 Gene3D G3DSA:3.40.109.10 NADH Oxidase
299 523 InterPro IPR000415 Nitroreductase-like
416 515 SUPERFAMILY SSF55469 FMN-dependent nitroreductase-like
416 515 InterPro IPR000415 Nitroreductase-like
304 512 CDD cd02142 McbC_SagB-like_oxidoreductase
7 531 PANTHER PTHR42741 NITROREDUCTASE FAMILY PROTEIN

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3943
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.355
1 0.253