Protein profile

PA3978

hypothetical protein

Genome: NC_002516.2

Gene: PA3978 podJ_2 GUL26_00220 CAZ10_26700 PAERUG_P19_London_7_VIM_2_05_10_02948 IPC1295_14540 GNQ48_15370 L4V69_08430 Structure source: AlphaFold UniProt G3XD26 UniProt Q51469
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Amino acids 182
Annotations 1
Features 18
PDB binders 0
Druggability 0.768

Overview

Basic information about this protein and its source genome.

Accession
PA3978
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3978 podJ_2 GUL26_00220 CAZ10_26700 PAERUG_P19_London_7_VIM_2_05_10_02948 IPC1295_14540 GNQ48_15370 L4V69_08430
Status
annotated
Amino acids
182
Structure source
AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
32.292
Human E-value
4.4e-07
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.768
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
97 128 Pfam PF08238 Sel1 repeat
97 128 InterPro IPR006597 Sel1-like repeat
61 96 Pfam PF08238 Sel1 repeat
61 96 InterPro IPR006597 Sel1-like repeat
1 23 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
8 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
34 135 SUPERFAMILY SSF81901 HCP-like
22 182 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
61 96 SMART SM00671 sel1
97 132 SMART SM00671 sel1
97 132 InterPro IPR006597 Sel1-like repeat
17 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 23 SignalP_EUK SignalP-noTM SignalP-noTM
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
21 165 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
21 165 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
37 136 PANTHER PTHR11102 SEL-1-LIKE PROTEIN

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3978
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.768
3 0.585