Protein profile

PA3981

hypothetical protein

Genome: NC_002516.2

Gene: PA3981 Structure source: AlphaFold UniProt Q9HX38
Export view
Amino acids 340
Annotations 2
Features 9
PDB binders 0
Druggability 0.622

Overview

Basic information about this protein and its source genome.

Accession
PA3981
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA3981
Status
annotated
Amino acids
340
Structure source
AlphaFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0005524 Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.622
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
  • GO:0005524 Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
319 340 MobiDBLite mobidb-lite consensus disorder prediction
113 316 Pfam PF02562 PhoH-like protein
113 316 InterPro IPR003714 PhoH-like protein
112 293 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
112 293 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
4 319 PANTHER PTHR30473 PROTEIN PHOH
110 314 FunFam G3DSA:3.40.50.300:FF:000013 PhoH family ATPase
110 316 Gene3D G3DSA:3.40.50.300 -
110 316 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA3981
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
6 0.622
2 0.518
4 0.205