Protein profile

PA4017

hypothetical protein

Genome: NC_002516.2

Gene: PA4017 Structure source: Experimental + AlphaFold UniProt Q9HX10
Export view
Amino acids 213
Annotations 0
Features 7
PDB binders 0
Druggability 0.89

Overview

Basic information about this protein and its source genome.

Accession
PA4017
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4017
Status
annotated
Amino acids
213
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
30.734
Human E-value
1.24e-21
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.89
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
1 213 Gene3D G3DSA:3.40.50.720 -
57 156 Pfam PF08732 HIM1
57 156 InterPro IPR014843 Protein Him1/Fmp52
6 213 PANTHER PTHR14097 OXIDOREDUCTASE HTATIP2
6 208 CDD cd05250 CC3_like_SDR_a
5 198 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains
5 198 InterPro IPR036291 NAD(P)-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 2A35
X-ray 1.50 Å A,B
100.0% 1-213
PDBe RCSB PDBj File
Viewing
AlphaFold PA4017
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.89

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 7.83 0.415
2 3.93 0.155
3 1.16 0.009