Protein profile

PA4040

hypothetical protein

Genome: NC_002516.2

Gene: PA4040 Structure source: AlphaFold UniProt Q9HWY7
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Amino acids 335
Annotations 0
Features 12
PDB binders 0
Druggability 0.938

Overview

Basic information about this protein and its source genome.

Accession
PA4040
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4040
Status
annotated
Amino acids
335
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.938
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
6 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
70 252 Pfam PF14238 Domain of unknown function (DUF4340)
70 252 InterPro IPR025641 Domain of unknown function DUF4340
1 21 SignalP_EUK SignalP-noTM SignalP-noTM
22 335 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 5 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
7 24 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
99 120 MobiDBLite mobidb-lite consensus disorder prediction
304 335 MobiDBLite mobidb-lite consensus disorder prediction
17 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
99 113 MobiDBLite mobidb-lite consensus disorder prediction

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4040
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.93
5 0.515