Protein profile

PA4182

hypothetical protein

Genome: NC_002516.2

Gene: PA4182 Structure source: AlphaFold UniProt Q9HWJ9
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Amino acids 212
Annotations 0
Features 9
PDB binders 0
Druggability 0.562

Overview

Basic information about this protein and its source genome.

Accession
PA4182
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4182
Status
annotated
Amino acids
212
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.562
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MYLPSHFEESDPQALHALIRDYPLGLLVSHGEAGLDANHLPFELSPAKGAQGTLEAHVARNNPVWSELRDGDEVLVVFRAGDAYISPQWYPSKQEHHRQVPTWNYRVVHAHGRVRIRDDERYVRGLVARLTRTHEATQETPWKMTDGPADYIDEMLRLIVGIEIEITRLVGKFKLSQNKEARDIRGASAALLARGEQAIGAAMDDCAARRDG

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
1 211 PANTHER PTHR35802 PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2
1 211 InterPro IPR007396 Transcriptional regulator PAI 2-type
9 192 SUPERFAMILY SSF50475 FMN-binding split barrel
1 212 PIRSF PIRSF010372 PaiB
1 212 InterPro IPR007396 Transcriptional regulator PAI 2-type
1 209 Gene3D G3DSA:2.30.110.10 -
1 209 InterPro IPR012349 FMN-binding split barrel
1 168 Pfam PF04299 Putative FMN-binding domain
1 168 InterPro IPR007396 Transcriptional regulator PAI 2-type

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4182
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.562
3 0.259