Protein profile

PA4318

hypothetical protein

Genome: NC_002516.2

Gene: PA4318 Structure source: AlphaFold UniProt Q9HW83
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Amino acids 265
Annotations 1
Features 10
PDB binders 0
Druggability 0.702

Overview

Basic information about this protein and its source genome.

Accession
PA4318
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4318
Status
annotated
Amino acids
265
Structure source
AlphaFold
GO
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.702
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MTPRWLASDFPRHGPPMPPNAAARLVAPASRPGAEVLDTHYHVETPEGIDLLLRPAGVVPRALAYTIDLCIRGLIMLVLMLGLAFLGKLGAGLGLLLTFIMTWWYMVLFEVLNQGRSPGKQMMGLRVVHDDGTPVGWAASLLRNLLRFADILPFGYALGLLCCLNHPAFKRLGDIAAGTLVVYREPELSRPSLPDVEPQLPPFPMSLEEQRAFLGFAERGAALSSARREELAGILAEPLGVEPVRAQAEINGIARGFLGLRQESA

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
69 86 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
56 176 Pfam PF06271 RDD family
56 176 InterPro IPR010432 RDD
1 61 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
113 265 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
87 91 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
91 113 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
92 112 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
39 263 PANTHER PTHR38480 SLR0254 PROTEIN
62 86 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4318
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.702
2 0.226