Protein profile

PA4323

hypothetical protein

Genome: NC_002516.2

Gene: PA4323 Structure source: AlphaFold UniProt Q9HW78
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Amino acids 443
Annotations 0
Features 17
PDB binders 0
Druggability 0.928

Overview

Basic information about this protein and its source genome.

Accession
PA4323
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4323
Status
annotated
Amino acids
443
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.928
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

17 records
Show feature table
Start End DB Term Name
112 441 PANTHER PTHR33608 BLL2464 PROTEIN
1 5 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
35 57 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 22 SignalP_EUK SignalP-TM SignalP-TM
6 28 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
58 443 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
232 394 Gene3D G3DSA:3.40.50.410 von Willebrand factor, type A domain
232 394 InterPro IPR036465 von Willebrand factor A-like domain superfamily
38 57 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
199 283 Pfam PF01882 Protein of unknown function DUF58
199 283 InterPro IPR002881 Domain of unknown function DUF58
6 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 28 Phobius SIGNAL_PEPTIDE Signal peptide region
29 37 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
22 28 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
240 365 SUPERFAMILY SSF53300 vWA-like
240 365 InterPro IPR036465 von Willebrand factor A-like domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4323
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
11 0.928
6 0.228
1 0.219