Protein profile

PA4348

hypothetical protein

Genome: NC_002516.2

Gene: PA4348 Structure source: AlphaFold UniProt Q9HW53
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Amino acids 261
Annotations 0
Features 10
PDB binders 0
Druggability 0.755

Overview

Basic information about this protein and its source genome.

Accession
PA4348
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4348
Status
annotated
Amino acids
261
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.755
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MRREPIVLFDNGSHQCLCFDDLVSGEGVQSNQFLIVDNGQYLLLDPGGDLTYTPLSLELSKRFPLQELDYIFASHQDPDIIAALDKWLLHTRARVICSKLWARFLPHLTANYLAVSHGINTYDRVMPLPDRGQAIALGDCSLKAIPAHFLHSVGNFQLYDPVSKILFSGDMGASLVDDAAPVSDFAAHIQYMDGFHRRYMAANKICRLWARMVRDMDVEMIVPQHGRPFVGKEMISAFLYWIENLECGIDLLGPDDYRMPG

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
28 226 Pfam PF19583 ODP family beta lactamase
28 226 InterPro IPR045761 ODP domain
5 243 Gene3D G3DSA:3.60.15.10 -
5 243 InterPro IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
6 259 PANTHER PTHR43041 HYDROLASE, METALLO-BETA-LACTAMASE SUPERFAMILY
29 225 SMART SM00849 Lactamase_B_5a
29 225 InterPro IPR001279 Metallo-beta-lactamase
12 243 SUPERFAMILY SSF56281 Metallo-hydrolase/oxidoreductase
12 243 InterPro IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
26 241 CDD cd07709 flavodiiron_proteins_MBL-fold

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4348
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.755
3 0.522