Protein profile

PA4382

hypothetical protein

Genome: NC_002516.2

Gene: PA4382 Structure source: AlphaFold UniProt Q9HW20
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Amino acids 264
Annotations 0
Features 29
PDB binders 0
Druggability 0.933

Overview

Basic information about this protein and its source genome.

Accession
PA4382
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4382
Status
annotated
Amino acids
264
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.933
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

29 records
Show feature table
Start End DB Term Name
100 122 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
16 26 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
100 229 Pfam PF01569 PAP2 superfamily
100 229 InterPro IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
173 178 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
1 31 SignalP_EUK SignalP-TM SignalP-TM
19 230 SUPERFAMILY SSF48317 Acid phosphatase/Vanadium-dependent haloperoxidase
19 230 InterPro IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
120 153 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
68 88 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
209 228 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
229 264 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
71 88 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
27 31 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
100 119 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
154 172 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
89 99 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
179 197 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
154 172 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
16 254 Gene3D G3DSA:1.20.144.10 Phosphatidic acid phosphatase type 2/haloperoxidase
1 15 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 31 Phobius SIGNAL_PEPTIDE Signal peptide region
198 208 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
32 67 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
13 35 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
37 227 CDD cd03396 PAP2_like_6
211 228 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
179 201 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
238 258 MobiDBLite mobidb-lite consensus disorder prediction

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4382
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.933
7 0.236