Protein profile

PA4384

hypothetical protein

Genome: NC_002516.2

Gene: PA4384 Structure source: AlphaFold UniProt Q9HW18
Amino acids 228
Annotations 0
Features 17
PDB binders 0
Druggability 0.213

Overview

Basic information about this protein and its source genome.

Accession
PA4384
Gene
PA4384
Status
annotated
Amino acids
228
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.213
Structure
Pocket

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

17 records
Show feature table
Start End DB Term Name
4 14 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
32 187 Pfam PF08857 Putative ParB-like nuclease
32 187 InterPro IPR014956 Putative ParB-like nuclease
25 154 Gene3D G3DSA:3.90.1530.10 -
15 228 PIRSF PIRSF029669 UCP029669
15 228 InterPro IPR016932 Uncharacterised conserved protein UCP029669
155 217 Gene3D G3DSA:1.10.8.10 -
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 18 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
15 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
19 228 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
29 225 SUPERFAMILY SSF110849 ParB/Sulfiredoxin
29 225 InterPro IPR036086 ParB/Sulfiredoxin superfamily
1 18 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
30 189 CDD cd16390 ParB_N_Srx_like
30 189 InterPro IPR014956 Putative ParB-like nuclease

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4384
AlphaFold full sequence Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.213