Overview
Basic information about this protein and its source genome.
- Accession
- PA4384
- Gene
- PA4384
- Status
- annotated
- Amino acids
- 228
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Unknown
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 4 | 14 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. |
| 32 | 187 | Pfam | PF08857 | Putative ParB-like nuclease |
| 32 | 187 | InterPro | IPR014956 | Putative ParB-like nuclease |
| 25 | 154 | Gene3D | G3DSA:3.90.1530.10 | - |
| 15 | 228 | PIRSF | PIRSF029669 | UCP029669 |
| 15 | 228 | InterPro | IPR016932 | Uncharacterised conserved protein UCP029669 |
| 155 | 217 | Gene3D | G3DSA:1.10.8.10 | - |
| 1 | 3 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. |
| 1 | 18 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM |
| 15 | 18 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. |
| 1 | 18 | Phobius | SIGNAL_PEPTIDE | Signal peptide region |
| 19 | 228 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. |
| 29 | 225 | SUPERFAMILY | SSF110849 | ParB/Sulfiredoxin |
| 29 | 225 | InterPro | IPR036086 | ParB/Sulfiredoxin superfamily |
| 1 | 18 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM |
| 30 | 189 | CDD | cd16390 | ParB_N_Srx_like |
| 30 | 189 | InterPro | IPR014956 | Putative ParB-like nuclease |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA4384
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 3 | 0.213 |