Protein profile

PA4424

hypothetical protein

Genome: NC_002516.2

Gene: PA4424 Structure source: AlphaFold UniProt Q9HVZ1

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Amino acids 125

Annotations 1

Features 12

PDB binders 0

Druggability 0.626

Overview

Basic information about this protein and its source genome.

Accession: PA4424
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA4424
Status: annotated
Amino acids: 125
Structure source: AlphaFold

GO:0003676 Binding to a nucleic acid.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.626

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0003676 Binding to a nucleic acid.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records

Show feature table

Start	End	DB	Term	Name
13	125	Gene3D	G3DSA:3.40.1350.10	-
13	125	InterPro	IPR011856	tRNA endonuclease-like domain superfamily
14	105	Pfam	PF02021	Uncharacterised protein family UPF0102
14	105	InterPro	IPR003509	UPF0102 protein YraN-like
7	124	NCBIfam	TIGR00252	YraN family protein
7	124	InterPro	IPR003509	UPF0102 protein YraN-like
8	118	SUPERFAMILY	SSF52980	Restriction endonuclease-like
8	118	InterPro	IPR011335	Restriction endonuclease type II-like
5	124	PANTHER	PTHR34039	UPF0102 PROTEIN YRAN
5	124	InterPro	IPR003509	UPF0102 protein YraN-like
7	118	Hamap	MF_00048	UPF0102 protein YraN [yraN].
7	118	InterPro	IPR003509	UPF0102 protein YraN-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA4424	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.626