Protein profile

PA4440

hypothetical protein

Genome: NC_002516.2

Gene: PA4440 Structure source: AlphaFold UniProt Q9HVX5

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Amino acids 209

Annotations 1

Features 7

PDB binders 0

Druggability 0.755

Overview

Basic information about this protein and its source genome.

Accession: PA4440
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA4440
Status: annotated
Amino acids: 209
Structure source: AlphaFold

GO:0009058 A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.755

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0009058 A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records

Show feature table

Start	End	DB	Term	Name
1	207	Gene3D	G3DSA:3.40.50.1820	alpha/beta hydrolase
1	207	InterPro	IPR029058	Alpha/Beta hydrolase fold
6	203	SUPERFAMILY	SSF53474	alpha/beta-Hydrolases
6	203	InterPro	IPR029058	Alpha/Beta hydrolase fold
88	139	Pfam	PF00975	Thioesterase domain
88	139	InterPro	IPR001031	Thioesterase
28	192	PANTHER	PTHR42103	ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA4440	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.755